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Dr Felix Aplin

Dr Felix Aplin

Postdoctoral Fellow

- Doctor of Philosophy: School of Medicine, Dentistry & Health Sciences, University of Melbourne.

- Bachelor of Science with Honours (Neuroscience), Australian National University.

Medicine & Health
School of Biomedical Sciences

Felix Aplin is a postdoctoral fellow at the Translational Neuroscience Facility, Faculty of Medicine & Health at UNSW Sydney. He holds a PhD in Medical Sciences from the University of Melbourne, and has completed research fellowships at Johns Hopkins Hospital and Hannover Medical School. He is currently a chief investigator at UNSW exploring new treatments for chronic pain, and he also works in neural engineering, medical bionics, brain-machine interfaces, and neural degeneration. He is particularly interested in using technology to connect with, and repair, our nervous systems.
Phone
0402286711
E-mail
f.aplin@unsw.edu.au
  • Books | 2021
    Kral A; Aplin F; Maier H, 2021, Prostheses for the Brain: Introduction to Neuroprosthetics,
  • Book Chapters | 2023
    Aplin FP; Fridman GY, 2023, 'Implantable Direct Current Neural Modulation', in Handbook of Neuroengineering, Springer Nature Singapore, pp. 787 - 823,
    Book Chapters | 2022
    Aplin FP; Fridman GY, 2022, 'Implantable Direct Current Neural Modulation', in Handbook of Neuroengineering, Springer Nature Singapore, pp. 1 - 37,
  • Journal articles | 2024
    Luu BL; Trinh T; Finn HT; Aplin FP; Gandevia SC; Héroux ME; Butler JE, 2024, 'Pain tolerance and the thresholds of human sensory and motor axons to single and repetitive bursts of kilohertz-frequency stimulation', Journal of Physiology,
    Journal articles | 2024
    Su TF; Hamilton JD; Guo Y; Potas JR; Shivdasani MN; Moalem-Taylor G; Fridman GY; Aplin FP, 2024, 'Peripheral direct current reduces naturally evoked nociceptive activity at the spinal cord in rodent models of pain', Journal of Neural Engineering, 21,
    Journal articles | 2021
    Thakur R; Aplin FP; Fridman GY, 2021, 'A hydrogel-based microfluidic nerve cuff for neuromodulation of peripheral nerves', Micromachines, 12,
    Journal articles | 2019
    Aplin FP; Fridman GY, 2019, 'Implantable direct current neural modulation: Theory, feasibility, and efficacy', Frontiers in Neuroscience, 13,
    Journal articles | 2019
    Aplin FP; Singh D; Della Santina CC; Fridman GY, 2019, 'Combined ionic direct current and pulse frequency modulation improves the dynamic range of vestibular canal stimulation', Journal of Vestibular Research: Equilibrium and Orientation, 29, pp. 89 - 96,
    Journal articles | 2019
    Aplin FP; Singh D; Santina CCD; Fridman GY, 2019, 'Ionic Direct Current Modulation for Combined Inhibition/Excitation of the Vestibular System', IEEE Transactions on Biomedical Engineering, 66, pp. 775 - 783,
    Journal articles | 2019
    Manca M; Glowatzki E; Roberts DC; Fridman GY; Aplin FP, 2019, 'Ionic direct current modulation evokes spike-rate adaptation in the vestibular periphery', Scientific Reports, 9,
    Journal articles | 2018
    Yang F; Anderson M; He S; Stephens K; Zheng Y; Chen Z; Raja SN; Aplin F; Guan Y; Fridman G, 2018, 'Differential expression of voltage-gated sodium channels in afferent neurons renders selective neural block by ionic direct current', Science Advances, 4,
    Journal articles | 2016
    Aplin FP; Fletcher EL; Luu CD; Vessey KA; Allen PJ; Guymer RH; Shepherd RK; Shivdasani MN, 2016, 'Stimulation of a suprachoroidal retinal prosthesis drives cortical responses in a feline model of retinal degeneration', Investigative Ophthalmology and Visual Science, 57, pp. 5216 - 5229,
    Journal articles | 2016
    Aplin FP; Vessey KA; Luu CD; Guymer RH; Shepherd RK; Fletcher EL, 2016, 'Retinal changes in an ATP-induced model of retinal degeneration', Frontiers in Neuroanatomy, 10,
    Journal articles | 2016
    Ho T; Aplin FP; Jobling AI; Phipps JA; De Iongh RU; Greferath U; Vessey KA; Fletcher EL, 2016, 'Localization and Possible Function of P2X Receptors in Normal and Diseased Retinae', Journal of Ocular Pharmacology and Therapeutics, 32, pp. 509 - 517,
    Journal articles | 2014
    Aplin FP; Luu CD; Vessey KA; Guymer RH; Shepherd RK; Fletcher EL, 2014, 'ATP-induced photoreceptor death in a feline model of retinal degeneration', Investigative Ophthalmology and Visual Science, 55, pp. 8319 - 8329,
    Journal articles | 2014
    Vessey KA; Greferath U; Aplin FP; Jobling AI; Phipps JA; Ho T; De Iongh RU; Fletcher EL, 2014, 'Adenosine triphosphate-induced photoreceptor death and retinal remodeling in rats', Journal of Comparative Neurology, 522, pp. 2928 - 2950,
  • Preprints | 2023
    Su T; Hamilton J; Guo Y; Potas J; Shivdasani M; Moalem-Taylor G; Fridman G; Aplin F, 2023, Peripheral direct current suppresses physiologically evoked nociceptive responses at the spinal cord in rodent models of pain,
    Conference Papers | 2020
    Cheng C; Aplin FP; Fridman GY, 2020, 'A microfluidic system integrated with shape memory alloy valves for a safe direct current delivery system', in Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS, pp. 3544 - 3548,

Grant #GNT1187416: A novel approach for peripheral neuromodulation: Using ionic direct current to treat chronic pain
• Funding Organisation: National Health and Medical Research Council
• Role on Project: Chief Investigator B
• Grant Award Period: June 2020 - January 2023

Festival of Dangerous Ideas 2022 Invited Speaker presented 17-18th of September at the Sydney Carriageworks to a live (200+) audience, as part of the “Unthinkable” program (talk titled “Building Better Brains”.

UNSOMNIA 2021 Recipient and Speaker awarded on 13 April 2021. UNSOMNIA is a fully funded media grant that combines continued professional development with the opportunity to present research in a public forum.

Mavis and Ian Rowe Prize for Retinal Diseases research (AU$2,300) awarded on 24 March 2013 for research on retinal prosthesis function in degenerate retina.

R.B. McComas Research Scholarship (AU$25,000 per annum) awarded between 28 February 2011 and 28 February 2015 during Ph.D. candidature.