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Dr Omid Faridani

Dr Omid Faridani

Senior Lecturer
Medicine & Health
School of Biomedical Sciences

I am a group leader at the School of Medical Sciences and a visiting group leader at the Garvan Institute of Medical Research. My research program uses state-of-the-art technology in the field of "single cell omics" to tackle hard-to-crack problems of cancer treatment. My focus is pancreatic cancer and other solid tumours. The main goal of the lab is to tailor treatment for each patient.

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Phone
+61293858796
  • Journal articles | 2023
    Baumann V; Athanasiou AT; Faridani OR; Schwerdtfeger AR; Wallner B; Steinborn R, 2023, 'Corrigendum: Identification of extremely GC-rich micro RNAs for RT-qPCR data normalization in human plasma, (Front. Genet, (2023), 13, (1058668), 10.3389/fgene.2022.1058668)', Frontiers in Genetics, 14,
    Journal articles | 2023
    Baumann V; Athanasiou AT; Faridani OR; Schwerdtfeger AR; Wallner B; Steinborn R, 2023, 'Identification of extremely GC-rich micro RNAs for RT-qPCR data normalization in human plasma', Frontiers in Genetics, 13,
    Journal articles | 2023
    Salignon J; Faridani OR; Miliotis T; Janssens GE; Chen P; Zarrouki B; Sandberg R; Davidsson P; Riedel CG, 2023, 'Age prediction from human blood plasma using proteomic and small RNA data: a comparative analysis', Aging, 15, pp. 5240 - 5265,
    Journal articles | 2023
    Schnegg-Kaufmann AS; Thoms JAI; Bhuyan GS; Hampton HR; Vaughan L; Rutherford K; Kakadia PM; Lee HM; Johansson Beves EMV; Failes TW; Arndt GM; Koval J; Lindeman R; Warburton P; Rodriguez-Meira A; Mead AJ; Unnikrishnan A; Davidson S; Polizzotto MN; Hertzberg M; Papaemmanuil E; Bohlander SK; Faridani OR; Jolly CJ; Zanini F; Pimanda JE, 2023, 'Contribution of mutant HSC clones to immature and mature cells in MDS and CMML, and variations with AZA therapy', Blood, 141, pp. 1316 - 1321,
    Journal articles | 2022
    Schnegg-Kaufmann A; Thoms J; Bhuyan GS; Henry H; Vaughan L; Rutherford K; Kakadia P; Johansson E; Failes T; Greg A; Koval J; Lindeman R; Warburton P; Rodriguez-Meira A; Mead A; Unnikrishnan A; Bohlander S; Pappaemmanuil E; Faridani O; Jolly C; Zanini F; Pimanda J, 2022, 'P748: SINGLE CELL GENOTYPING OF MATCHED BONE MARROW AND PERIPHERAL BLOOD CELLS IN TREATMENT NAIVE AND AZA-TREATED MDS AND CMML', HemaSphere, 6, pp. 643 - 644,
    Journal articles | 2022
    Thoms JAI; Schnegg-Kaufmann A; Bhuyan GS; Hampton HR; Vaughan L; Rutherford K; Kakadia PM; Lee HM; Johansson E; Failes TW; Arndt GM; Koval J; Davidson S; Lindeman R; Warburton P; Rodriguez-Meira A; Mead AJ; Unnikrishnan A; Hertzberg M; Polizzotto MN; Papaemmanuil E; Bohlander SK; Faridani O; Jolly CJ; Zanini F; Pimanda JE, 2022, 'Clinical Response to Azacytidine (AZA) Is Associated with Increased Contribution from Mutated Blood Progenitors: Insights from Single Cell Genotyping of Matched Stem/Progenitor and Mature Blood Cells from MDS/CMML Patients Pre- and Post-AZA Treatment', Blood, 140, pp. 9751 - 9752,
    Journal articles | 2022
    Von Grothusen C; Frisendahl C; Modhukur V; Lalitkumar PG; Peters M; Faridani OR; Salumets A; Boggavarapu NR; Gemzell-Danielsson K, 2022, 'Uterine fluid microRNAs are dysregulated in women with recurrent implantation failure', Human Reproduction, 37, pp. 734 - 746,
    Journal articles | 2021
    Godakumara K; Ord J; Lättekivi F; Dissanayake K; Viil J; Boggavarapu NR; Faridani OR; Jääger K; Velthut-Meikas A; Jaakma Ãœ; Salumets A; Fazeli A, 2021, 'Trophoblast derived extracellular vesicles specificallyÌýalter the transcriptome of endometrial cells and may constitute a critical component of embryo-maternal communication', Reproductive Biology and Endocrinology, 19,
    Journal articles | 2021
    Zheleznyakova GY; Piket E; Needhamsen M; Hagemann-Jensen M; Ekman D; Han Y; James T; Khademi M; Al Nimer F; Scicluna P; Huang J; Kockum I; Faridani OR; Olsson T; Piehl F; Jagodic M, 2021, 'Small noncoding RNA profiling across cellular and biofluid compartments and their implications for multiple sclerosis immunopathology', Proceedings of the National Academy of Sciences of the United States of America, 118,
    Journal articles | 2020
    Hagemann-Jensen M; Ziegenhain C; Chen P; Ramsköld D; Hendriks GJ; Larsson AJM; Faridani OR; Sandberg R, 2020, 'Single-cell RNA counting at allele and isoform resolution using Smart-seq3', Nature Biotechnology, 38, pp. 708 - 714,
    Journal articles | 2020
    Ramsköld D; Luo S; Wang YC; Li R; Deng Q; Faridani OR; Daniels GA; Khrebtukova I; Loring JF; Laurent LC; Schroth GP; Sandberg R, 2020, 'Author Correction: Full-length mRNA-Seq from single-cell levels of RNA and individual circulating tumor cells (Nature Biotechnology, (2012), 30, 8, (777-782), 10.1038/nbt.2282)', Nature Biotechnology, 38, pp. 374,
    Journal articles | 2020
    Zheleznyakova GY; Piket E; Needhamsen M; Hagemann-Jensen M; Ekman D; Khademi M; Nimer FA; Scicluna P; Faridani O; Olsson T; Piehl F; Jagodic M, 2020, 'Profiling of small non-coding RNAs across cellular and biofluid compartments: implications for multiple sclerosis immunopathology', ,
    Journal articles | 2019
    Larsson AJM; Johnsson P; Hagemann-Jensen M; Hartmanis L; Faridani OR; Reinius B; Segerstolpe Ã…; Rivera CM; Ren B; Sandberg R, 2019, 'Genomic encoding of transcriptional burst kinetics', Nature, 565, pp. 251 - 254,
    Journal articles | 2018
    Hagemann-Jensen M; Abdullayev I; Sandberg R; Faridani OR, 2018, 'Small-seq for single-cell small-RNA sequencing', Nature Protocols, 13, pp. 2407 - 2424,
    Journal articles | 2016
    Faridani OR; Abdullayev I; Hagemann-Jensen M; Schell JP; Lanner F; Sandberg R, 2016, 'Single-cell sequencing of the small-RNA transcriptome', Nature Biotechnology, 34, pp. 1264 - 1266,
    Journal articles | 2016
    Simonson OE; Mougiakakos D; Heldring N; Bassi G; Johansson HJ; Dalén M; Jitschin R; Rodin S; Corbascio M; El Andaloussi S; Wiklander OPB; Nordin JZ; Skog J; Romain C; Koestler T; Hellgren-Johansson L; Schiller P; Joachimsson P-O; Hägglund H; Mattsson M; Lehtiö J; Faridani OR; Sandberg R; Korsgren O; Krampera M; Weiss DJ; Grinnemo K-H; Le Blanc K, 2016, 'In Vivo Effects of Mesenchymal Stromal Cells in Two Patients With Severe Acute Respiratory Distress Syndrome', Stem Cells Translational Medicine, 5, pp. 845 - 845,
    Journal articles | 2015
    Faridani OR; Sandberg R, 2015, 'Putting cells in their place', Nature biotechnology, 33, pp. 490 - 491,
    Journal articles | 2015
    Simonson OE; Mougiakakos D; Heldring N; Bassi G; Johansson HJ; Dalén M; Jitschin R; Rodin S; Corbascio M; El Andaloussi S; Wiklander OPB; Nordin JZ; Skog J; Romain C; Koestler T; Hellgren-Johansson L; Schiller P; Joachimsson PO; Hägglund H; Mattiasmattsson M; Lehtiö J; Faridani OR; Sandberg R; Korsgren O; Krampera M; Weiss DJ; Grinnemo KH; Le Blanc K, 2015, 'In vivo effects of mesenchymal stromal cells in two patients with severe acute respiratory distress syndrome', Stem Cells Translational Medicine, 4, pp. 1199 - 1213,
    Journal articles | 2014
    Callegari S; Gastaldello S; Faridani OR; Masucci MG, 2014, 'Epstein-Barr virus encoded microRNAs target SUMO-regulated cellular functions', FEBS Journal, 281, pp. 4935 - 4950,
    Journal articles | 2014
    Picelli S; Faridani OR; Björklund AK; Winberg G; Sagasser S; Sandberg R, 2014, 'Full-length RNA-seq from single cells using Smart-seq2', Nature Protocols, 9, pp. 171 - 181,
    Journal articles | 2013
    Picelli S; Björklund AK; Faridani OR; Sagasser S; Winberg G; Sandberg R, 2013, 'Smart-seq2 for sensitive full-length transcriptome profiling in single cells', Nature Methods, 10, pp. 1096 - 1100,
    Journal articles | 2012
    Ramsköld D; Luo S; Wang YC; Li R; Deng Q; Faridani OR; Daniels GA; Khrebtukova I; Loring JF; Laurent LC; Schroth GP; Sandberg R, 2012, 'Full-length mRNA-Seq from single-cell levels of RNA and individual circulating tumor cells', Nature Biotechnology, 30, pp. 777 - 782,
    Journal articles | 2011
    Arefian E; Kiani J; Soleimani M; Shariati SAM; Aghaee-Bakhtiari SH; Atashi A; Gheisari Y; Ahmadbeigi N; Banaei-Moghaddam AM; Naderi M; Namvarasl N; Good L; Faridani OR, 2011, 'Analysis of microRNA signatures using size-coded ligation-mediated PCR', Nucleic Acids Research, 39, pp. e80 - e80,
    Journal articles | 2010
    Gastaldello S; Hildebrand S; Faridani O; Callegari S; Palmkvist M; Di Guglielmo C; Masucci MG, 2010, 'A deneddylase encoded by Epstein-Barr virus promotes viral DNA replication by regulating the activity of cullin-RING ligases', Nature Cell Biology, 12, pp. 351 - 361,
    Journal articles | 2008
    Faridani OR; Mcinerney GM; Gradin K; Good L, 2008, 'Specific ligation to double-stranded RNA for analysis of cellular RNA::RNA interactions', Nucleic Acids Research, 36, pp. e99,
    Journal articles | 2007
    Nikravesh A; Dryselius R; Faridani OR; Goh S; Sadeghizadeh M; Behmanesh M; Ganyu A; Klok EJ; Zain R; Good L, 2007, 'Antisense PNA accumulates in Escherichia coli and mediates a long post-antibiotic effect', Molecular Therapy, 15, pp. 1537 - 1542,
    Journal articles | 2006
    Faridani OR; Nikravesh A; Pandey DP; Gerdes K; Good L, 2006, 'Competitive inhibition of natural antisense Sok-RNA interactions activates Hok-mediated cell killing in Escherichia coli', Nucleic Acids Research, 34, pp. 5915 - 5922,
  • Preprints | 2024
    Tarbier M; Mackowiak SD; Sekar V; Bonath F; Yapar E; Fromm B; Faridani OR; Biryukova I; Friedländer MR, 2024, Landscape of microRNA and target expression variation and covariation in single mouse embryonic stem cells,
    Preprints | 2022
    Schnegg-Kaufmann A; Thoms J; Bhuyan GS; Hampton H; Vaughan L; Rutherford K; Kakadia P; Johansson E; Failes T; Arndt G; Koval J; Lindeman R; Warburton P; Rodriguez-Meira A; Mead A; Unnikrishnan A; Bohlander S; Papaemmanuil E; Faridani O; Jolly C; Zanini F; Pimanda J, 2022, Single cell genotyping of matched bone marrow and peripheral blood cells in treatment naive and AZA-treated MDS and CMML,
    Conference Abstracts | 2022
    Von Grothusen C; Frisendahl C; Vijayachitra M; Parameswaran Grace L; Peters M; Faridani O; Andres S; Rao Boggavarapu N; Gemzell-Danielsson K, 2022, 'P-420 Dysregulated microRNAs in uterine fluid from women with recurrent implantation failure are linked to endometrial receptivity and implantation', in Human Reproduction, Oxford University Press (OUP), Vol. 37,
    Conference Abstracts | 2020
    Zheleznyakova G; Piket E; Needhamsen M; Hagemann-Jensen M; Ekman D; Khademi M; Al Nimer F; Scicluna P; Faridani O; Olsson T; Piehl F; Jagodic M, 2020, 'Profiling of small non-coding rnas across cellular and biofluid compartments in patients with multiple sclerosis', in MULTIPLE SCLEROSIS JOURNAL, SAGE PUBLICATIONS LTD, ELECTR NETWORK, Vol. 26, pp. 183 - 184, presented at 8th Joint ACTRIMS-ECTRIMS Meeting (MSVirtual), ELECTR NETWORK, 11 September 2020 - 13 September 2020,
    Preprints | 2019
    Hagemann-Jensen M; Ziegenhain C; Chen P; Ramsköld D; Hendriks G-J; Larsson AJM; Faridani O; Sandberg R, 2019, Single-cell RNA counting at allele- and isoform-resolution using Smart-seq3,
    Conference Abstracts | 2019
    Zheleznyakova G; Piket E; Needhamsen M; Hagemann-Jensen M; Faridani O; Marabita F; Khademi M; Piehl F; Olsson T; Jagodic M, 2019, 'Genome-wide small-noncoding RNA analysis in patients with multiple sclerosis', in MULTIPLE SCLEROSIS JOURNAL, SAGE PUBLICATIONS LTD, SWEDEN, Stockholm, Vol. 25, pp. 726 - 726, presented at 35th Congress of the European-Committee-for-Treatment-and-Research-in-Multiple-Sclerosis (ECTRIMS) / 24th Annual Conference of Rehabilitation in MS, SWEDEN, Stockholm, 11 September 2019 - 13 September 2019,

Cancer Council NSW

Cellular GenomicsÌýFutures Institute grant

CAG Cancer grant

I haveÌýreceived the 2019 Pathfinders Award for the work of developing a device that enriches CTCs from the blood of cancer patients.Ìý

For more information please visitÌýwww.faridanilab.com.